On the uniqueness of limit cycles for Li\'enard equation: the legacy of G. Sansone

We give an account of the results about limit cycle's uniqueness for Li\'enard equations, from Levinson-Smith's one to the most recent ones. We present a new uniqueness theorem in the line of Sansone-Massera's geometrical approach.Comment: 2 figure

Limit cycle's uniqueness for a class of planar dynamical systems

A uniqueness theorem for limit cycles of a class of plane differential system is proved. The main result is applicable to secord order O.D.E.'s with dissipative term depending both on the position and the velocity

Disinvestment in healthcare: An overview of HTA agencies and organizations activities at European level

Background: In an era of a growing economic pressure for all health systems, the interest for "disinvestment" in healthcare increased. In this context, evidence based approaches such as Health Technology Assessment (HTA) are needed both to invest and to disinvest in health technologies. In order to investigate the extent of application of HTA in this field, methodological projects/frameworks, case studies, dissemination initiatives on disinvestment released by HTA agencies and organizations located in Europe were searched. Methods: In July 2015, the websites of HTA agencies and organizations belonging to the European network for HTA (EUnetHTA) and the International Network of Agencies for HTA (INAHTA) were accessed and searched through the use of the term "disinvestment". Retrieved deliverables were considered eligible if they reported methodological projects/frameworks, case studies and dissemination initiatives focused on disinvestment in healthcare. Results: 62 HTA agencies/organizations were accessed and eight methodological projects/frameworks, one case study and one dissemination initiative were found starting from 2007. With respect to methodological projects/frameworks, two were delivered in Austria, one in Italy, two in Spain and three in U.K. As for the case study and the dissemination initiative, both came from U.K. The majority of deliverables were aimed at making an overview of existing disinvestment approaches and at identifying challenges in their introduction. Conclusions: Today, in a healthcare context characterized by resource scarcity and increasing service demand, "disinvestment" from low-value services and reinvestment in high-value ones is a key strategy that may be supported by HTA. The lack of evaluation of technologies in use, in particular at the end of their lifecycle, may be due to the scant availability of frameworks and guidelines for identification and assessment of obsolete technologies that was shown by our work. Although several projects were carried out in different countries, most remain constrained to the field of research. Disinvestment is a relatively new concept in HTA that could pose challenges also from a methodological point of view. To tackle these challenges, it is necessary to construct experiences at international level with the aim to develop new methodological approaches to produce and grow evidence on disinvestment policies and practices

Prevalence and molecular characterization of Aereomonas spp. in ready-to-eat foods in Italy

A survey was carried out in Italy to ascertain the prevalence of Aeromonas spp. in ready-to-eat foods (vegetables, cheeses, meat products, and ice creams) and the level of molecular heterogeneity of the isolates found by macrorestriction analysis of genomic DNA with pulsed-field gel electrophoresis (PFGE). In total, 46 (14.4%) of the 320 food samples examined were found positive for Aeromonas spp. The highest percentages of isolation were discovered in vegetables, particularly lettuce (45.0%), endive (40.0%), and rucola (20.0%). Ricotta was the only cheese type analyzed that showed a high frequency of isolation (45.0%). Among meat products, salami and raw ham (25.0% of samples positive) and, to a lesser extent, baloney (5.0%) were found positive for Aeromonas spp. Aeromonas hydrophila was the most common isolate from foods of animal origin, whereas Aeromonas caviae was the dominant species in vegetables. No motile aeromonads were found in ice cream samples. Aeromonas isolates showed a high level of genetic heterogeneity, because 24 PFGE patterns were identified among 27 A. hydrophila strains and 20 PFGE patterns were found in 23 A. caviae isolates. In conclusion, consumers of ready-to-eat foods in Italy are regularly exposed to many genetically distinct strains of A. hydrophila and A. caviae without evident signs of malaise, and therefore, few of these strains, if any, are likely to be pathogenic

Verbi locativi in italiano come varianti di verbi supporto

In questo articolo discuteremo la nozione di "carrier verbs" (secondo la definizione del linguista americano Zellig Harris) o di "light verbs" (come denominata all'inizio del XX secolo da Otto Jespersen). La nostra cornice teorica è rappresentata dal lessico-grammatica di Maurice Gross, una teoria iniziata negli anni settanta a partire dalla sintassi del francese sulle basi matematiche già individuate per la lingua inglese da Zellig Harris. In particolare, discuteremo di come alcuni verbi locativi dell'italiano possano essere usati come verbi supporto (secondo la definizione data da Gross dei "light verbs" harrisiani) e assumano il ruolo sintattico una volta attribuito dai grammatici greci e latini alla copula esse.En aquest article discutirem la noció de "carrier verbs" (segons la definició del lingüista americà Zellig Harris) o de "light verbs" (segons la denominació que Otto Jespersen n'havia donat a principi del segle XX). El nostre marc teòric de referència és el lèxic-gramàtica de Maurice Gross, una teoria començada els anys setanta a partir de la sintaxi del francès en les bases matemàtiques ja individuades per a la llengua anglesa per Zelling Harris. Concretament, tractarem de com alguns verbs locatius de l'italià es poden emprar com a verbs de suport (tal com Gross va definir els "light verbs" harrisians) i de com assumeixen el paper sintàctic que els gramàtics grecs i llatins atribuïen a la còpula esse.In this article we aim at discussing the notion of carrier verbs (according to the definition provided by the American linguist Zellig Harris) or of light verbs (as defined at the beginning of the twentieth century by Otto Jespersen). Our theoretical framework is represented by Maurice Gross' lexicon-grammar, a theory developed during the seventies on the French syntax and directly inspired by Zellig Harris' mathematical grammar of English. Particularly, we are going to discuss of how some Italian locative verbs can be used as support verbs (according to the definition which Maurice Gross has given of the harrisian light verbs) and can play the syntactic role traditionally given to the copula esse by the Greek and Latin grammarians

Genomics knowledge and attitudes among European public health professionals. Results of a cross-sectional survey

Background The international public health (PH) community is debating the opportunity to incorporate genomic technologies into PH practice. A survey was conducted to assess attitudes of the European Public Health Association (EUPHA) members towards their role in the implementation of public health genomics (PHG), and their knowledge and attitudes towards genetic testing and the delivery of genetic services. Methods EUPHA members were invited via monthly newsletter and e-mail to take part in an online survey from February 2017 to January 2018. A descriptive analysis of knowledge and attitudes was conducted, along with a univariate and multivariate analysis of their determinants. Results Five hundred and two people completed the questionnaire, 17.9% were involved in PHG activities. Only 28.9% correctly identified all medical conditions for which there is (or not) evidence for implementing genetic testing; over 60% thought that investing in genomics may divert economic resources from social and environmental determinants of health. The majority agreed that PH professionals may play different roles in incorporating genomics into their activities. Better knowledge was associated with positive attitudes towards the use of genetic testing and the delivery of genetic services in PH (OR = 1.48; 95% CI 1.01–2.18). Conclusions Our study revealed quite positive attitudes, but also a need to increase awareness on genomics among European PH professionals. Those directly involved in PHG activities tend to have a more positive attitude and better knowledge; however, gaps are also evident in this group, suggesting the need to harmonize practice and encourage greater exchange of knowledge among professionals